The origin and efficient derivation of embryonic stem cells in the mouse

By explanting tissues isolated microsurgically from implanting strain 129 mouse blastocysts individually on STO feeder cells we have established that embryonic stem (ES) cells originate from the epiblast (primitive ectoderm). Isolated early epiblasts yielded ES cell lines at a substantially higher f...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Brook, F. A., Gardner, R. L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5709
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