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Embryonic stem cells and somatic cells differ in mutation frequency and type
Pluripotent embryonic stem (ES) cells have been used to produce genetically modified mice as experimental models of human genetic diseases. Increasingly, human ES cells are being considered for their potential in the treatment of injury and disease. Here we have shown that mutation in murine ES cell...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122567/ https://ncbi.nlm.nih.gov/pubmed/11891338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062527199 |
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