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Embryonic stem cells and somatic cells differ in mutation frequency and type

Pluripotent embryonic stem (ES) cells have been used to produce genetically modified mice as experimental models of human genetic diseases. Increasingly, human ES cells are being considered for their potential in the treatment of injury and disease. Here we have shown that mutation in murine ES cell...

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Bibliografiska uppgifter
Huvudupphovsmän: Cervantes, Rachel B., Stringer, James R., Shao, Changshun, Tischfield, Jay A., Stambrook, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2002
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC122567/
https://ncbi.nlm.nih.gov/pubmed/11891338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062527199
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