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Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts.

Limitation of lifespan in replicative senescence is related to oxidative stress, which is probably both the cause and consequence of impaired mitochondrial respiratory function. The respiration of senescent human diploid fibroblasts was analysed by high-resolution respirometry. To rule out cell-cycl...

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Detalhes bibliográficos
Main Authors: Hutter, Eveline, Renner, Kathrin, Pfister, Gerald, Stöckl, Petra, Jansen-Dürr, Pidder, Gnaiger, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224220/
https://ncbi.nlm.nih.gov/pubmed/15018610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040095
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