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High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia
Mitochondria are confronted with low oxygen levels in the microenvironment within tissues; yet, isolated mitochondria are routinely studied under air-saturated conditions that are effectively hyperoxic, increase oxidative stress, and may impair mitochondrial function. Under hypoxia, on the other han...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The National Academy of Sciences
2000
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC27151/ https://ncbi.nlm.nih.gov/pubmed/11005877 |
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