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Regulation of mitochondrial ROS production by HIC‐5: a common feature of oncogene‐induced senescence and tumor invasiveness?

Transformation by the ras oncogene can result in promotion of metastasis as well as induction of senescence via increased tissue remodeling, for example, by matrix metalloproteases. Increased production of mitochondrial reactive oxygen species (mtROS) via NADPH oxidase 4 (NOX4) is implicated in this...

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Vydáno v:FEBS J
Hlavní autoři: Doppler, Wolfgang, Jansen‐Dürr, Pidder
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850634/
https://ncbi.nlm.nih.gov/pubmed/30680933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14746
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