Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Cellular senescence is considered a major tumour-suppressor mechanism in mammals, and many oncogenic insults, such as the activation of the ras proto-oncogene, trigger initiation of the senescence programme. Although it was shown that activation of the senescence programme involves the up-regulation...

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Detaylı Bibliyografya
Asıl Yazarlar: Zwerschke, Werner, Mazurek, Sybille, Stöckl, Petra, Hütter, Eveline, Eigenbrodt, Erich, Jansen-Dürr, Pidder
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2003
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223775/
https://ncbi.nlm.nih.gov/pubmed/12943534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030816
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