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Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.
Cellular senescence is considered a major tumour-suppressor mechanism in mammals, and many oncogenic insults, such as the activation of the ras proto-oncogene, trigger initiation of the senescence programme. Although it was shown that activation of the senescence programme involves the up-regulation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223775/ https://ncbi.nlm.nih.gov/pubmed/12943534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030816 |
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