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Modulation of type M(2) pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein

We report here that the E7 oncoprotein encoded by the oncogenic human papillomavirus (HPV) type 16 binds to the glycolytic enzyme type M(2) pyruvate kinase (M2-PK). M2-PK occurs in a tetrameric form with a high affinity to its substrate phosphoenolpyruvate and a dimeric form with a low affinity to p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zwerschke, Werner, Mazurek, Sybille, Massimi, Paola, Banks, Lawrence, Eigenbrodt, Erich, Jansen-Dürr, Pidder
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC15456/
https://ncbi.nlm.nih.gov/pubmed/9990017
Tagiau: Ychwanegu Tag
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