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Inactivation of p53 but Not p73 by Adenovirus Type 5 E1B 55-Kilodalton and E4 34-Kilodalton Oncoproteins

The adenovirus E1B 55-kDa and E4 34-kDa oncoproteins bind and inactivate the p53 tumor suppressor gene product, resulting in cell transformation. A recently discovered cellular protein, p73, shows extensive similarities to p53 in structure and function. Here we show that the simultaneous transient e...

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Sonraí Bibleagrafaíochta
Main Authors: Roth, Judith, König, Claudia, Wienzek, Sandra, Weigel, Silke, Ristea, Susanne, Dobbelstein, Matthias
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC110260/
https://ncbi.nlm.nih.gov/pubmed/9765388
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