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Induction of Transformation and p53-Dependent Apoptosis by Adenovirus Type 5 E4orf6/7 cDNA

Adenovirus (Ad) E4orf6/7, one of the early gene products of human Ads, forms a stable complex with the cellular transcription factor E2F to activate transcription from the Ad E2 promoter. E2F cDNAs have growth-promoting and apoptosis-inducing activities when overexpressed in cells. We cloned Ad5 E4o...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Yamano, Shigeru, Tokino, Takashi, Yasuda, Motoaki, Kaneuchi, Masanori, Takahashi, Minoru, Niitsu, Yoshiro, Fujinaga, Kei, Yamashita, Toshiharu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10095-10103.1999
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