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Induction of Transformation and p53-Dependent Apoptosis by Adenovirus Type 5 E4orf6/7 cDNA

Adenovirus (Ad) E4orf6/7, one of the early gene products of human Ads, forms a stable complex with the cellular transcription factor E2F to activate transcription from the Ad E2 promoter. E2F cDNAs have growth-promoting and apoptosis-inducing activities when overexpressed in cells. We cloned Ad5 E4o...

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Detalhes bibliográficos
Main Authors: Yamano, Shigeru, Tokino, Takashi, Yasuda, Motoaki, Kaneuchi, Masanori, Takahashi, Minoru, Niitsu, Yoshiro, Fujinaga, Kei, Yamashita, Toshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113061/
https://ncbi.nlm.nih.gov/pubmed/10559324
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