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Induction of Transformation and p53-Dependent Apoptosis by Adenovirus Type 5 E4orf6/7 cDNA

Adenovirus (Ad) E4orf6/7, one of the early gene products of human Ads, forms a stable complex with the cellular transcription factor E2F to activate transcription from the Ad E2 promoter. E2F cDNAs have growth-promoting and apoptosis-inducing activities when overexpressed in cells. We cloned Ad5 E4o...

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Bibliographic Details
Published in:J Virol
Main Authors: Yamano, Shigeru, Tokino, Takashi, Yasuda, Motoaki, Kaneuchi, Masanori, Takahashi, Minoru, Niitsu, Yoshiro, Fujinaga, Kei, Yamashita, Toshiharu
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559324/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10095-10103.1999
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