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Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells
5-Lipoxygenase (5-LO) is a tightly regulated enzyme in the synthesis of bioactive lipids from arachidonic acid. Here, we demonstrate that 5-LO is regulated by caspases, which are signaling molecules that control critical biological processes by means of specific limited proteolysis. Cell splitting o...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201604/ https://ncbi.nlm.nih.gov/pubmed/16135563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505991102 |
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