Biochemical and Immunogenic Characterization of Soluble Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers Expressed by Semliki Forest Virus

The current lack of envelope glycoprotein immunogens that elicit broadly neutralizing antibody responses remains a major challenge for human immunodeficiency virus type 1 (HIV-1) vaccine development. However, the recent design and construction of stable soluble gp140 trimers have shown that some neu...

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Detalhes bibliográficos
Main Authors: Forsell, Mattias N. E., Li, Yuxing, Sundbäck, Maria, Svehla, Krisha, Liljeström, Peter, Mascola, John R., Wyatt, Richard, Hedestam, Gunilla B. Karlsson
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193613/
https://ncbi.nlm.nih.gov/pubmed/16103142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.10902-10914.2005
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