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HIV-1 Envelope Glycoprotein Trimer Immunogenicity Elicited in the Presence of Human CD4 Alters the Neutralization Profile

The HIV-1 envelope glycoproteins (Env) gp120 and gp41 are the sole virally derived components on the surface of the virus. These glycoproteins mediate receptor binding and entry and are targets for neutralizing antibodies. The most highly validated protein region on Env that is a target for broadly...

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Hlavní autoři: Forsell, Mattias N.E., McKee, Krisha, Feng, Yu, Mascola, John R., Wyatt, Richard T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208562/
https://ncbi.nlm.nih.gov/pubmed/25245278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2014.0104
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