Characterization of Antibody Responses Elicited by Human Immunodeficiency Virus Type 1 Primary Isolate Trimeric and Monomeric Envelope Glycoproteins in Selected Adjuvants

We previously reported that soluble, stable YU2 gp140 trimeric human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein immunogens could elicit improved breadth of neutralization against HIV-1 isolates compared to monomeric YU2 gp120 proteins. In this guinea pig immunization study, we sough...

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Autors principals: Li, Y., Svehla, K., Mathy, N. L., Voss, G., Mascola, J. R., Wyatt, R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346938/
https://ncbi.nlm.nih.gov/pubmed/16415019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1414-1426.2006
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