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Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice
Direct evidence that hyperglycemia, rather than concomitant increases in known risk factors, induces atherosclerosis is lacking. Most diabetic mice do not exhibit a higher degree of atherosclerosis unless the development of diabetes is associated with more severe hyperlipidemia. We hypothesized that...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1190371/ https://ncbi.nlm.nih.gov/pubmed/16127462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24819 |
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