Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice

Guidelines to reduce cardiovascular risk in diabetes include aggressive LDL lowering, but benefits are attenuated compared with those in patients without diabetes. Consistent with this, we have reported in mice that hyperglycemia impaired atherosclerosis regression. Aldose reductase (AR) is thought...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yuan, Chujun, Hu, Jiyuan, Parathath, Saj, Grauer, Lisa, Cassella, Courtney Blachford, Bagdasarov, Svetlana, Goldberg, Ira J., Ramasamy, Ravichandran, Fisher, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110315/
https://ncbi.nlm.nih.gov/pubmed/29891593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0156
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