Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice

Guidelines to reduce cardiovascular risk in diabetes include aggressive LDL lowering, but benefits are attenuated compared with those in patients without diabetes. Consistent with this, we have reported in mice that hyperglycemia impaired atherosclerosis regression. Aldose reductase (AR) is thought...

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Bibliografische gegevens
Gepubliceerd in:Diabetes
Hoofdauteurs: Yuan, Chujun, Hu, Jiyuan, Parathath, Saj, Grauer, Lisa, Cassella, Courtney Blachford, Bagdasarov, Svetlana, Goldberg, Ira J., Ramasamy, Ravichandran, Fisher, Edward A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2018
Onderwerpen:
Complications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110315/
https://ncbi.nlm.nih.gov/pubmed/29891593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0156
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