Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice

Guidelines to reduce cardiovascular risk in diabetes include aggressive LDL lowering, but benefits are attenuated compared with those in patients without diabetes. Consistent with this, we have reported in mice that hyperglycemia impaired atherosclerosis regression. Aldose reductase (AR) is thought...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Yuan, Chujun, Hu, Jiyuan, Parathath, Saj, Grauer, Lisa, Cassella, Courtney Blachford, Bagdasarov, Svetlana, Goldberg, Ira J., Ramasamy, Ravichandran, Fisher, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2018
Fag:
Complications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110315/
https://ncbi.nlm.nih.gov/pubmed/29891593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0156
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