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Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase ι

Because of the near geometric identity of Watson-Crick (W-C) G·C and A·T base pairs, a given DNA polymerase forms the four possible correct base pairs with nearly identical catalytic efficiencies. However, human DNA polymerase ι (Polι), a member of the Y family of DNA polymerases, exhibits a marked...

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Autori principali: Johnson, Robert E., Prakash, Louise, Prakash, Satya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180782/
https://ncbi.nlm.nih.gov/pubmed/16014707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503859102
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