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Role of Hoogsteen Edge Hydrogen Bonding at Template Purines in Nucleotide Incorporation by Human DNA Polymerase ι

Human DNA polymerase ι (Pol ι) differs from other DNA polymerases in that it exhibits a marked template specificity, being more efficient and accurate opposite template purines than opposite pyrimidines. The crystal structures of Pol ι with template A and incoming dTTP and with template G and incomi...

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Detalhes bibliográficos
Main Authors: Johnson, Robert E., Haracska, Lajos, Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592827/
https://ncbi.nlm.nih.gov/pubmed/16914729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00851-06
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