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Replication across template T/U by human DNA polymerase-ι
Human DNA polymerase-ι (Polι) incorporates correct nucleotides opposite template purines with a much higher efficiency and fidelity than opposite template pyrimidines. In fact, the fidelity opposite template T is so poor that Polι inserts an incorrect dGTP approximately 10 times better than it inser...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030472/ https://ncbi.nlm.nih.gov/pubmed/19604477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.04.011 |
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