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DNA synthesis across an abasic lesion by human DNA polymerase-ι
Abasic (AP) sites are among the most abundant DNA lesions formed in human cells and they present a strong block to replication. DNA polymerase ι (Polι) is one of the few DNA Pols that does not follow the A-rule opposite an abasic site. We present here three structures of human Polι in complex with D...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703454/ https://ncbi.nlm.nih.gov/pubmed/19368886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.02.015 |
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