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DNA synthesis across an abasic lesion by yeast Rev1 DNA polymerase

Abasic (AP) sites are amongst the most abundant DNA lesions in humans and they present a strong block to replication. They are also highly mutagenic because when the replicative DNA polymerases do manage to insert a nucleotide opposite the lesion they prefer to insert an A. Rev1, a member of the Y-f...

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Библиографические подробности
Главные авторы: Nair, Deepak T., Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127253/
https://ncbi.nlm.nih.gov/pubmed/21167175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.016
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