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DNA synthesis across an abasic lesion by yeast Rev1 DNA polymerase
Abasic (AP) sites are amongst the most abundant DNA lesions in humans and they present a strong block to replication. They are also highly mutagenic because when the replicative DNA polymerases do manage to insert a nucleotide opposite the lesion they prefer to insert an A. Rev1, a member of the Y-f...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127253/ https://ncbi.nlm.nih.gov/pubmed/21167175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.016 |
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