Downstream E-Box–mediated Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Transcription: Evidence for an Endogenous Mechanism of Transcriptional Repression

Regulation of the hTERT gene encoding the telomerase catalytic subunit plays an important role in human cell senescence, immortalization, and carcinogenesis. By examining the activity of various deleted or mutated hTERT promoter fragments, we show that an E-box element downstream of the transcriptio...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Biol Cell
Hauptverfasser:	Horikawa, Izumi, Cable, P. LouAnn, Mazur, Sharlyn J., Appella, Ettore, Afshari, Cynthia A., Barrett, J. Carl
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12181331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E01-11-0107
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!