Downstream E-Box–mediated Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Transcription: Evidence for an Endogenous Mechanism of Transcriptional Repression

Regulation of the hTERT gene encoding the telomerase catalytic subunit plays an important role in human cell senescence, immortalization, and carcinogenesis. By examining the activity of various deleted or mutated hTERT promoter fragments, we show that an E-box element downstream of the transcriptio...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Biol Cell
Päätekijät:	Horikawa, Izumi, Cable, P. LouAnn, Mazur, Sharlyn J., Appella, Ettore, Afshari, Cynthia A., Barrett, J. Carl
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Cell Biology 2002
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12181331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E01-11-0107
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