Downstream E-Box–mediated Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Transcription: Evidence for an Endogenous Mechanism of Transcriptional Repression

Regulation of the hTERT gene encoding the telomerase catalytic subunit plays an important role in human cell senescence, immortalization, and carcinogenesis. By examining the activity of various deleted or mutated hTERT promoter fragments, we show that an E-box element downstream of the transcriptio...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Horikawa, Izumi, Cable, P. LouAnn, Mazur, Sharlyn J., Appella, Ettore, Afshari, Cynthia A., Barrett, J. Carl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12181331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E01-11-0107
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!