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Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT

Human telomerase reverse transcriptase (hTERT) is a catalytic subunit of human telomerase and is a critical determinant of the enzymatic activity of telomerase. Expression of hTERT is known to be regulated mainly at the transcriptional level. In the present study, using transient expression assays,...

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Main Authors: Fujimoto, Kohtaro, Kyo, Satoru, Takakura, Masahiro, Kanaya, Taro, Kitagawa, Yasuhide, Itoh, Hideaki, Takahashi, Morinobu, Inoue, Masaki
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC102701/
https://ncbi.nlm.nih.gov/pubmed/10871406
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