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Multiple hematopoietic defects and delayed globin switching in Ikaros null mice

We have previously reported the structure of a chromatin remodeling complex (PYR complex) with Ikaros as its DNA binding subunit that is specifically present in adult murine and human hematopoietic cells. We now show that homozygous Ikaros “knockout” (null) mice lack the PYR complex, demonstrating t...

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Autors principals: Lopez, Rocio A., Schoetz, Stuti, DeAngelis, Kathryn, O'Neill, David, Bank, Arthur
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC117352/
https://ncbi.nlm.nih.gov/pubmed/11805317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022412699
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