Multiple hematopoietic defects and delayed globin switching in Ikaros null mice
We have previously reported the structure of a chromatin remodeling complex (PYR complex) with Ikaros as its DNA binding subunit that is specifically present in adult murine and human hematopoietic cells. We now show that homozygous Ikaros “knockout” (null) mice lack the PYR complex, demonstrating t...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022412699 |
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