Multiple hematopoietic defects and delayed globin switching in Ikaros null mice

We have previously reported the structure of a chromatin remodeling complex (PYR complex) with Ikaros as its DNA binding subunit that is specifically present in adult murine and human hematopoietic cells. We now show that homozygous Ikaros “knockout” (null) mice lack the PYR complex, demonstrating t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Lopez, Rocio A., Schoetz, Stuti, DeAngelis, Kathryn, O'Neill, David, Bank, Arthur
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022412699
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