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Human SWI/SNF-Associated PRMT5 Methylates Histone H3 Arginine 8 and Negatively Regulates Expression of ST7 and NM23 Tumor Suppressor Genes

Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in controlling cell growth and proliferation remains obscure. We have recently shown that PRMT5 can interact with flag-tagged BRG1- and hBRM-based hSWI/SNF chromatin remodele...

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Autors principals: Pal, Sharmistha, Vishwanath, Sheethal N., Erdjument-Bromage, Hediye, Tempst, Paul, Sif, Saïd
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC522266/
https://ncbi.nlm.nih.gov/pubmed/15485929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9630-9645.2004
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