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Multiple hematopoietic defects and delayed globin switching in Ikaros null mice
We have previously reported the structure of a chromatin remodeling complex (PYR complex) with Ikaros as its DNA binding subunit that is specifically present in adult murine and human hematopoietic cells. We now show that homozygous Ikaros “knockout” (null) mice lack the PYR complex, demonstrating t...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117352/ https://ncbi.nlm.nih.gov/pubmed/11805317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022412699 |
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