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Akt Maintains Cell Size and Survival by Increasing mTOR-dependent Nutrient Uptake
In multicellular organisms, constituent cells depend on extracellular signals for growth, proliferation, and survival. When cells are withdrawn from growth factors, they undergo apoptosis. Expression of constitutively active forms of the serine/threonine kinase Akt/PKB can prevent apoptosis upon gro...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117312/ https://ncbi.nlm.nih.gov/pubmed/12134068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-12-0584 |
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