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Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment

We have proposed that tolerance can be maintained through the induction, by Treg cells, of a tolerogenic microenvironment within tolerated tissues that inhibits effector cell activity but which supports the generation of further Treg cells by “infectious tolerance.” Two important components of this...

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Autors principals: Howie, Duncan, Waldmann, Herman, Cobbold, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147234/
https://ncbi.nlm.nih.gov/pubmed/25221554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00409
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