Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation.

The nef gene of human and simian immunodeficiency viruses is critical for AIDS pathogenesis. Its function in vivo is unknown, but in vitro natural isolates of Nef down-regulate expression of the cell surface CD4 molecule, a component of the T cell antigen receptor and the viral receptor, by accelera...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Greenberg, M E, Bronson, S, Lock, M, Neumann, M, Pavlakis, G N, Skowronski, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170300/
https://ncbi.nlm.nih.gov/pubmed/9384576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.23.6964
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados