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Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70.

Signaling by the antigen receptor of T lymphocytes initiates different developmental transitions, each of which require the tyrosine kinase ZAP70. Previous studies with agonist and antagonist peptides have indicated that ZAP70 might respond differently to different structures of the TCR-CD3 complex...

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Detalhes bibliográficos
Main Authors: Graef, I A, Holsinger, L J, Diver, S, Schreiber, S L, Crabtree, G R
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170194/
https://ncbi.nlm.nih.gov/pubmed/9312021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.18.5618
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