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ZAP-70 Tyrosine Kinase Is Required for LFA-1–dependent T Cell Migration

The ZAP-70 tyrosine kinase is essential for T cell activation by the T cell receptor. We show that ZAP-70 is also required for migration of T cells that is dependent on the integrin LFA-1. Invasion of TAM2D2 T cell hybridoma cells into fibroblast monolayers, which is LFA-1–dependent, was blocked by...

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Hlavní autoři: Soede, Ron D.M., Wijnands, Yvonne M., Van Kouteren-Cobzaru, Ioana, Roos, Ed
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149357/
https://ncbi.nlm.nih.gov/pubmed/9732296
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