The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

An early stage in thymocyte development, after rearrangement of the β chain genes of the T cell receptor (TCR), involves expression of the pre-TCR complex and accompanying differentiation of CD4(−)CD8(−) double negative (DN) cells to CD4(+)CD8(+) double positive (DP) cells. The ZAP-70 and Syk tyrosi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cheng, Alec M., Negishi, Izumi, Anderson, Steven J., Chan, Andrew C., Bolen, Joseph, Loh, Dennis Y., Pawson, Tony
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9797
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