The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

An early stage in thymocyte development, after rearrangement of the β chain genes of the T cell receptor (TCR), involves expression of the pre-TCR complex and accompanying differentiation of CD4(−)CD8(−) double negative (DN) cells to CD4(+)CD8(+) double positive (DP) cells. The ZAP-70 and Syk tyrosi...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Alec M., Negishi, Izumi, Anderson, Steven J., Chan, Andrew C., Bolen, Joseph, Loh, Dennis Y., Pawson, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23271/
https://ncbi.nlm.nih.gov/pubmed/9275205
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