Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase.

Chimeric mice in which lymphocytes are deficient in the Syk tyrosine kinase have been created. Compared with Syk-positive controls, mice with Syk -/- lymphocytes display substantial depletion of intraepithelial gamma delta T cells in the skin and gut, with developmental arrest occurring after antige...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mallick-Wood, C A, Pao, W, Cheng, A M, Lewis, J M, Kulkarni, S, Bolen, J B, Rowley, B, Tigelaar, R E, Pawson, T, Hayday, A C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9704
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