Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase.

Chimeric mice in which lymphocytes are deficient in the Syk tyrosine kinase have been created. Compared with Syk-positive controls, mice with Syk -/- lymphocytes display substantial depletion of intraepithelial gamma delta T cells in the skin and gut, with developmental arrest occurring after antige...

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Autores principales: Mallick-Wood, C A, Pao, W, Cheng, A M, Lewis, J M, Kulkarni, S, Bolen, J B, Rowley, B, Tigelaar, R E, Pawson, T, Hayday, A C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC38493/
https://ncbi.nlm.nih.gov/pubmed/8790395
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