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Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Therapeutic vaccination has the potential to boost immune responses and enhance viral control during chronic infections. However, many therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T-cell responses is not always observed. To examine these i...

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Bibliografiske detaljer
Main Authors: Wherry, E. John, Blattman, Joseph N., Ahmed, Rafi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168795/
https://ncbi.nlm.nih.gov/pubmed/15994790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8960-8968.2005
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