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Retinoic Acid as a Vaccine Adjuvant Enhances CD8(+) T Cell Response and Mucosal Protection from Viral Challenge

Vaccine-induced memory T cells localized at mucosal sites can provide rapid protection from viral infection. All-trans-retinoic acid (ATRA) has been shown to act physiologically to induce the expression of gut-homing receptors on lymphocytes. We tested whether the administration of exogenous ATRA du...

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Autors principals: Tan, Xuefang, Sande, Jamie L., Pufnock, Jeffrey S., Blattman, Joseph N., Greenberg, Philip D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147979/
https://ncbi.nlm.nih.gov/pubmed/21653670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00781-11
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