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Alphavirus-Adjuvanted Norovirus-Like Particle Vaccines: Heterologous, Humoral, and Mucosal Immune Responses Protect against Murine Norovirus Challenge

The development of an effective norovirus vaccine likely requires the capacity to protect against infection with multiple norovirus strains. Advanced recombinant genetic systems and the recent discovery of a mouse-tropic norovirus strain (MNV) provide robust model systems for vaccine efficacy studie...

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Detalhes bibliográficos
Main Authors: LoBue, Anna D., Thompson, Joseph M., Lindesmith, Lisa, Johnston, Robert E., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655567/
https://ncbi.nlm.nih.gov/pubmed/19176631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01650-08
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