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Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Therapeutic vaccination has the potential to boost immune responses and enhance viral control during chronic infections. However, many therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T-cell responses is not always observed. To examine these i...

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Detalhes bibliográficos
Main Authors: Wherry, E. John, Blattman, Joseph N., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168795/
https://ncbi.nlm.nih.gov/pubmed/15994790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8960-8968.2005
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