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Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Therapeutic vaccination has the potential to boost immune responses and enhance viral control during chronic infections. However, many therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T-cell responses is not always observed. To examine these i...

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Autors principals: Wherry, E. John, Blattman, Joseph N., Ahmed, Rafi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168795/
https://ncbi.nlm.nih.gov/pubmed/15994790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8960-8968.2005
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