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Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination

Therapeutic vaccination has the potential to boost immune responses and enhance viral control during chronic infections. However, many therapeutic vaccination approaches have fallen short of expectations, and effective boosting of antiviral T-cell responses is not always observed. To examine these i...

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Библиографические подробности
Главные авторы: Wherry, E. John, Blattman, Joseph N., Ahmed, Rafi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168795/
https://ncbi.nlm.nih.gov/pubmed/15994790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8960-8968.2005
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