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Antiviral Effect of N-Butyldeoxynojirimycin against Bovine Viral Diarrhea Virus Correlates with Misfolding of E2 Envelope Proteins and Impairment of Their Association into E1-E2 Heterodimers

The iminosugar N-butyldeoxynojirimycin (NB-DNJ), an endoplasmic reticulum α-glucosidase inhibitor, has an antiviral effect against bovine viral diarrhea virus (BVDV). In this report, we investigate the molecular mechanism of this inhibition by studying the folding pathway of BVDV envelope glycoprote...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Branza-Nichita, Norica, Durantel, David, Carrouée-Durantel, Sandra, Dwek, Raymond A., Zitzmann, Nicole
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2001
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC114844/
https://ncbi.nlm.nih.gov/pubmed/11264342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3527-3536.2001
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