Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays

Crimean-Congo haemorrhagic fever virus (CCHFV) is a pathogen of increasing public health concern, being a widely distributed arbovirus and the causative agent of the potentially fatal Crimean-Congo haemorrhagic fever. Hazara virus (HAZV) is a genetically and serologically related virus that has been...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Beatrice E. Tyrrell, Abhinav Kumar, Bevin Gangadharan, Dominic Alonzi, Juliane Brun, Michelle Hill, Tehmina Bharucha, Andrew Bosworth, Victoria Graham, Stuart Dowall, Joanna L. Miller, Nicole Zitzmann
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-03-01
Schriftenreihe:	Pathogens
Schlagworte:	orthonairovirus nairovirus tick-borne virus antivirals imminosugars glycosylation
Online-Zugang:	https://www.mdpi.com/2076-0817/12/3/399
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!