Hybrid Vectors Based on Adeno-Associated Virus Serotypes 2 and 5 for Muscle-Directed Gene Transfer

Vectors based on hybrids consisting of adeno-associated virus types 2 (ITRs and Rep) and 5 (Cap) were evaluated for muscle-directed gene transfer (called AAV2/5). Evaluation in immune-competent mice revealed greater transduction efficacy with AAV2/5 than with AAV2 and no cross-neutralization between...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Hildinger, Markus, Auricchio, Alberto, Gao, Guangping, Wang, Lili, Chirmule, Narendra, Wilson, James M.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2001
Aiheet:	Gene Therapy
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6199-6203.2001
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