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Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle

Adeno-associated virus (AAV) is being developed as a vector capable of conferring long-term gene expression, which is useful in the treatment of chronic diseases. In most therapeutic applications, it is necessary to readminister the vector. This study characterizes the humoral immune response to AAV...

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Autori principali: Chirmule, Narendra, Xiao, Weidong, Truneh, Alemseged, Schnell, Michael A., Hughes, Joseph V., Zoltick, Philip, Wilson, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC111724/
https://ncbi.nlm.nih.gov/pubmed/10666273
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