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Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle

Adeno-associated virus (AAV) is being developed as a vector capable of conferring long-term gene expression, which is useful in the treatment of chronic diseases. In most therapeutic applications, it is necessary to readminister the vector. This study characterizes the humoral immune response to AAV...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Chirmule, Narendra, Xiao, Weidong, Truneh, Alemseged, Schnell, Michael A., Hughes, Joseph V., Zoltick, Philip, Wilson, James M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666273/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2420-2425.2000
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